Lester Dent’s 1933 The Man of Bronze is the first volume in the Doc Savage series. It was published under the house name Kenneth Robeson and was followed by 180 further adventures (penned mostly by Dent) until the title was cancelled in 1949. There have been further sequels and adaptations, as detailed here.
Trained from birth to be a paragon of human achievement, Clark “Doc” Savage is the Man of Bronze: a gigantic, extraordinarily talented genius who is monumentally wealthy as well. He uses his abilities to better the world.
Clark “Doc” Savage returns from a sojourn in his arctic Fortress of Solitude to face a tragedy. In his absence, his father, Clark Savage senior, has died of a mysterious illness. No sooner does Doc convene with his five chums on the 86th floor of a skyscraper to discuss the matter than a mysterious red-fingered sniper tries to murder Doc. Something is up!