Kaiju Girl Caramelise, Vol. 1 is the first collection of Spica Aoki’s eponymous Shoujo manga.
Kuroe Akaishi suffers from a rare (probably unique) medical condition so embarrassing that she hides it from her schoolmates. The condition is exacerbated by strong emotion, so she tries to avoid drama. She’s aloof and detached … or at least as detached as she can be given that her schoolmates mock and torment her.